My husband had his setons taken out last week after 6 months of remi. Decision to take them out is based on how remi helps and how far fistula are healing, is what our GI told usJust asked this to someone else with a seton - Do you know how they decided to take your seton out? My first one (a year ago) I only had for a few weeks, as they took it out for another surgery. This one I'm not sure when they'll take it out. I know that it's there to promote drainage so that a backup/abscess does not occur. I don't mind that - but sometimes, especially when it's seeping and/or I'm working out, it will make me chafe in between my cheeks and man does that hurt! It's like rug burn! Hoping since I'm on Remi now they may take it out soon?!