• Welcome to Crohn's Forum, a support group for people with all forms of IBD. While this community is not a substitute for doctor's advice and we cannot treat or diagnose, we find being able to communicate with others who have IBD is invaluable as we navigate our struggles and celebrate our successes. We invite you to join us.

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  1. Scipio

    Stelara Receives FDA Approval for Treatment of UC

    In addition to its previous approvals for Crohn's and psoriasis: https://www.fiercepharma.com/pharma/j-j-scores-stelara-ulcerative-colitis-nod-to-back-up-declining-remicade
  2. Scipio

    Anti-TNF Therapy Paradoxically Associated with Increased Risk of Developing Crohn's and UC

    Anti-TNF biologics linked to new-onset cases of IBD in patients receiving the drugs for non-IBD autoimmune diseases such as RA or psoriasis: https://onlinelibrary.wiley.com/doi/10.1111/apt.15370
  3. Scipio

    Reducing Red Meat Consumption in Crohn's Patients Did Not Lengthen Remission Period

    Randomized, controlled trial of high and low red meat consumption in Crohn's patients showed that lower meat consumption provided no benefit in extending remission periods. This is significant because it has been widely believed that consumption of red meat is "pro-inflammatory" and likely to...
  4. Scipio

    Anti-TNF Therapy is Linked to Lower Rate of Arterial Adverse Events

    ...as compared to thiopurine therapy: https://www.medpagetoday.com/gastroenterology/inflammatoryboweldisease/81818
  5. Scipio

    Commercial Gut Microbiota Test Found to be Flawed

    The data underlying the test and its health claims was found to be contaminated with bacteria from infants and pets. https://www.fiercebiotech.com/medtech/ubiome-s-underlying-data-tainted-samples-from-infants-pets-report
  6. Scipio

    Switching from Remicade to a Biosimilar Shows Mixed Results

    A study of switching from Remicade to a biosimilar shows mixed results: https://academic.oup.com/ecco-jcc/advance-article-abstract/doi/10.1093/ecco-jcc/jjz070/5446199 Excerpt: "Conclusions Switching from Remicade to CT-P13 might be associated with a higher risk of clinical relapse, although...
  7. Scipio

    Entyvio Tops Humira in a Head-to-Head Comparison Trial

    Entyvio was shown to be superior to Humira in inducing remission in an direct comparison trial in UC patients. This is the first head-to-head comparison of any of the biologics for IBD. All prior comparisons have been indirect - utilizing separate patient populations. I hope a lot more of...
  8. Scipio

    Risk of Pancreatitis is Increased Pedatirc IBD Treated With Azathioprine

    Risk of pancreatitis is increased 6-fold in kids with IBD who are treated with azathioprine: https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(18)30401-2/fulltext
  9. Scipio

    Medicare Coverage for Stelara

    Has anyone found a Medicare Advantage or Part D plan that provides good coverage for Stelara? The drug so far is working well for me, so I would rather not switch. And I'm currently employed and on the Janssen CarePath coverage, which is great -- only a $5 co-pay per dose. But looking ahead...
  10. Scipio

    Adding Stawberries to Diet Found to Decrease Gut Inflammation

    Using a mouse model for IBD: http://www.newswise.com/articles/strawberries-could-help-reduce-harmful-inflammation-in-the-colon From the article: "The researchers found that dietary consumption of whole strawberries at a dose equivalent to as low as three-quarters of a cup of strawberries per...
  11. Scipio

    School Stress May Trigger IBD Flares in Teens

    Disease onset and flares were higher at the start and end of academic terms: https://journals.lww.com/jpgn/Abstract/publishahead/Academic_Stress_May_Contribute_to_the_Onset_of.96789.aspx
  12. Scipio

    Use of anti-TNF IBD Drugs May Also Help Prevent Parkinson's

    Use of anti-TNF drugs to treat IBD may have the unintended benefit of lowering the risk of developing Parkinson's disease. https://jamanetwork.com/journals/jamaneurology/article-abstract/2679038?redirect=true
  13. Scipio

    Side Effects from Allopurinal More Likely in Black, Asians, and Hawaiians Than in Whites

    Allopurinal, a drug often given in conjunction with azathioprine or 6MP to lessen their side effects, can on rare occasions itself produce significant side effects. This research shows that African Americans, Asians, and Native Hawaiians are 3 to 7 times more likely to suffer severe skin side...
  14. Scipio

    Humira Biosimilar to be Available in Europe in 2018, in US not until 2023

    Patent disputes have been settled: https://www.businesswire.com/news/home/20180405005492/en/Samsung-Bioepis-Settles-Patent-Disputes-AbbVie-Clearing
  15. Scipio

    Microbiome Composition in Crohn's Patients Predicts Who Will Respond to Stelara Treatment

    http://mbio.asm.org/content/9/2/e02120-17.short?rss=1&related-urls=yes&legid=mbio;9/2/e02120-17 Baseline microbiota predicted treatment remission with a sensitivity of 81%, a specificity of 77% and an overall accuracy of 84%. Similarly, the microbiota model predicted treatment response with a...
  16. Scipio

    Certain Diabetes Drugs Increase Risk of IBD by 75%

    DPP-4 inhibitors (examples: Januvia and Tradjenta) increase IBD risk in Type-2 diabetes patients: https://www.mdedge.com/clinicalendocrinologynews/article/161422/diabetes/dpp-4-inhibitors-increase-ibd-risk-diabetes
  17. Scipio

    IBD Doubles Risk of Heart Attack...

    https://www.tctmd.com/news/inflammatory-bowel-disease-may-risk-mi-especially-young-people ...compared to controls without IBD. However, it was impossible to determine whether the risk is associated with the drugs used to treat IBD or with the disease itself since they almost always occur together.
  18. Scipio

    Progress on New Oral Anti-TNF

    Encouraging Phase II results from the development of an oral anti-TNF drug: https://www.fiercebiotech.com/biotech/israel-s-protalix-claims-early-success-oral-tnf-candidate
  19. Scipio

    Question for Parents of Kids with IBD

    Question: In your experience, what is the youngest age of patient at which GIs will perform a colonoscopy? Thanks for your help.
  20. Scipio

    Pericarditis?

    I have been diagnosed with Crohn's for over 5 years now. This year I also came down with pericarditis - a severe inflammation of the pericardium, the membrane that surrounds the heart. This in turn induced constrictive heart failure. My heart itself was fine, but the inflamed and thickened...
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