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  1. Lady Organic

    Flare after 6 month of succes with Humira, what's the next step?

    Hey guys, I entered full remission very rapidly in last January fallowing my first shots of Humira. Unfortunately, since a week, I notice a return of symptoms and I can now confirm its a flare in the rectum again. I will call my IBD team leater today to let them know. I have read Humira can be...
  2. Lady Organic

    Keeping Immunosuppressant along with Humira?

    Hey guys! im currently on humira and im doing super well. My GI would like that I stop 6-MP in the near future. his main concern is the fact that I had issues with pre-cancerous cervical lesions a few years back which required laser intervention. He doesnt like it at all and would prefer I stop...
  3. Lady Organic

    Fruit consumption is associated with alterations in microbial composition and lower rates of pouchitis

    ''Fruit consumption is associated with alterations in microbial composition and lower rates of pouchitis'' https://academic.oup.com/ecco-jcc/advance-article-abstract/doi/10.1093/ecco-jcc/jjz053/5368949?redirectedFrom=fulltext Abstract Background Patients with ulcerative colitis (UC) that...
  4. Lady Organic

    Anti-TNF Levels in Cord Blood at Birth are Associated with Anti-TNF Type

    Anti-TNF Levels in Cord Blood at Birth are Associated with Anti-TNF Type https://academic.oup.com/ecco-jcc/article/12/8/939/4996399 Abstract Background and Aims: Pregnancy guidelines for women with inflammatory bowel disease [IBD] provide recommendations regarding anti-TNF cessation during...
  5. Lady Organic

    Anti-TNF Levels in Cord Blood at Birth are Associated with Anti-TNF Type

    ''Anti-TNF Levels in Cord Blood at Birth are Associated with Anti-TNF Type'' https://academic.oup.com/ecco-jcc/article/12/8/939/4996399 Abstract Background and Aims: Pregnancy guidelines for women with inflammatory bowel disease [IBD] provide recommendations regarding anti-TNF cessation...
  6. Lady Organic

    Significant Association Between the Use of Different Proton Pump Inhibitors and Microscopic Colitis

    Significant Association Between the Use of Different Proton Pump Inhibitors and Microscopic Colitis: https://www.medscape.com/viewarticle/902429?src=wnl_tp10n_181108_mscpedit&uac=245498HV&impID=1794050&faf=1 Abstract Background: Microscopic colitis causes chronic watery diarrhoea and has...
  7. Lady Organic

    Effectiveness and safety of vedolizumab in adult patients with inflammatory bowel disease

    ''A real-world, long-term experience on effectiveness and safety of vedolizumab in adult patients with inflammatory bowel disease: The Cross Pennine study.'' https://www.ncbi.nlm.nih.gov/pubmed/30077465 Abstract BACKGROUND: Real-life data on vedolizumab effectiveness in inflammatory bowel...
  8. Lady Organic

    Ultraviolet Irradiation of Skin Alters the Faecal Microbiome Independently of Vitamin D in Mice.

    https://www.ncbi.nlm.nih.gov/pubmed/30103486 Abstract Reduced sunlight exposure has been associated with an increased incidence of Crohn's disease and ulcerative colitis. The effect of ultraviolet radiation (UVR) on the faecal microbiome and susceptibility to colitis has not been explored...
  9. Lady Organic

    The effect of vitamin D on intestinal inflammation and faecal microbiota in patients with ulcerative colitis.

    ''The effect of vitamin D on intestinal inflammation and faecal microbiota in patients with ulcerative colitis.'' https://www.ncbi.nlm.nih.gov/pubmed/29726893 Abstract Background and Aims: There is evidence vitamin D may be immunomodulatory and alter faecal microbiota, but results from...
  10. Lady Organic

    Low dose Naltrexone for induction of remission in inflammatory bowel disease patients.

    Low dose Naltrexone for induction of remission in inflammatory bowel disease patients. https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-018-1427-5 Abstract BACKGROUND: Around 30% of patients with inflammatory bowel disease (IBD) are refractory to current IBD drugs or...
  11. Lady Organic

    Benefits of Proactive Therapeutic Drug Monitoring in IBD

    ''Debating the Case for Proactive Therapeutic Drug Monitoring in IBD. May improve outcomes, but without evidence-based recommendations, not ready for prime time.'' https://www.medpagetoday.com/reading-room/aga/lower-gi/71626 Inflammatory bowel disease (IBD) is characterized as chronic...
  12. Lady Organic

    Webinar of QuBiologics upcoming Cronh's 2018 trial!

    here is the webinar with Dr Gunn, lead GI of the trial: https://www.youtube.com/watch?v=leVUjHJBbE4&feature=youtu.be
  13. Lady Organic

    Predictors of response to vedolizumab and ustekinumab in inflammatory bowel disease.

    https://www.ncbi.nlm.nih.gov/pubmed/29430672 Review article: predictors of response to vedolizumab and ustekinumab in inflammatory bowel disease. Abstract BACKGROUND: Increased knowledge of pathways involved in the pathogenesis of IBD has led to the development of new treatment options for...
  14. Lady Organic

    Efficacy of vedolizumab in fistulising Crohn's disease

    Efficacy of vedolizumab in fistulising Crohn's disease: Exploratory analyses of data from GEMINI 2.: Abstract Background and Aims: Medical management of fistulising Crohn's disease (CD) is constrained by the limited number of available therapies. We evaluated the efficacy of vedolizumab, a...
  15. Lady Organic

    Effects of Vedolizumab Therapy on Extraintestinal Manifestations in Inflammatory Bowel Disease

    very interesting article! https://link.springer.com/article/10.1007%2Fs10620-018-4971-1 Effects of Vedolizumab Therapy on Extraintestinal Manifestations in Inflammatory Bowel Disease. Abstract BACKGROUND: Approximately 15-20% of ulcerative colitis patients and 20-40% of those with Crohn's...
  16. Lady Organic

    Biologics with best safety profile?

    From what I understand about Biologics, Vedolizumab (Entivyo) has a better safety profile (serious and opportunistic infections, malignancies, etc), than Humira and Remicade, and doesnt come with the Black box warning. Wondering if Stelara is also considered with a better safety profile? I...
  17. Lady Organic

    Plasma microRNA Profile Differentiates Crohn's Colitis From Ulcerative Colitis.

    Plasma microRNA Profile Differentiates Crohn's Colitis From Ulcerative Colitis. https://www.ncbi.nlm.nih.gov/pubmed/29272478 Abstract Background: Inflammatory bowel disease (IBD) is commonly divided into 2 entities: Crohn's disease (CD) and ulcerative colitis (UC). Differentiating between...
  18. Lady Organic

    Stem cell local injections for perianal fistulas

    Long-term Efficacy and Safety of Stem Cell Therapy (Cx601) for Complex Perianal Fistulas in Patients With Crohn's Disease. https://www.ncbi.nlm.nih.gov/pubmed/29277560 Abstract BACKGROUND & AIMS: Therapies for perianal fistulas in patients with Crohn's disease (CD) are often ineffective in...
  19. Lady Organic

    Granulomas on biopsy and severity of Crohn's disease

    ''Epithelioid Granulomas Associate with Increased Severity and Progression of Crohn's Disease, Based on 6-year Follow Up.'' https://www.ncbi.nlm.nih.gov/pubmed/29277619 Abstract Epithelioid granulomas are characteristics of a subset of patients with Crohn's disease (CD), but their...
  20. Lady Organic

    Biologics and disease located in the rectum- experience please?

    I would like to know of your experience with a Biologic agent (Remicade, Humira, Stelara, Vedo, etc) and rectal healing. My disease always starts in the rectum and goes up in left colon and I am again in a debuting flare right now. I feel like I am done playing limbo with 6-mp. At 50mg it was...
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