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  1. Crohn2357

    “Sorriso Pharmaceuticals is creating the first orally-delivered anti-inflammatory drug for patients with IBD”

    https://www.utahbusiness.com/sorriso-pharmaceuticals-is-creating-the-first-orally-delivered-anti-inflammatory-drug-for-patients-with-ibd/
  2. Crohn2357

    Rapid Improvement and Remission in Patients With Refractory Ulcerative Colitis and Crohn’s Colitis After Direct Injection of Remestemcel-L by Colonosc

    https://finance.yahoo.com/news/rapid-improvement-remission-patients-refractory-231900721.html
  3. Crohn2357

    Can you eat dark chocolate and drink coffee without any problems?

    I can’t drink coffee, even a few sips give me abdominal pain, diarrhea etc.; but I can eat a little (10 grams?) dark chocolate (above 85% cocoa, the ones that don’t contain any dairy) every day. If I try to increase this amount, I get intestinal symptoms. I am curious if other Crohn’s patients...
  4. Crohn2357

    Food Additive Emulsifiers and Their Impact on Gut Microbiome, Permeability, and Inflammation: Mechanistic Insights in Inflammatory Bowel Disease

    Food Additive Emulsifiers and Their Impact on Gut Microbiome, Permeability, and Inflammation: Mechanistic Insights in Inflammatory Bowel Disease Aaron S Bancil, Alicia M Sandall, Megan Rossi, Benoit Chassaing, James O Lindsay, Kevin Whelan Journal of Crohn's and Colitis, Volume 15, Issue 6...
  5. Crohn2357

    Efficacy and safety of simultaneous treatment with two biologic medications in refractory Crohn's disease

    Aliment Pharmacol Ther 2020 Jun;51(11):1031-1038. doi: 10.1111/apt.15719.Epub 2020 Apr 24. Efficacy and safety of simultaneous treatment with two biologic medications in refractory Crohn's disease Edward Yang 1, Nicola Panaccione 2, Natalie Whitmire 1, Parambir S Dulai 1, Niels Vande Casteele 1...
  6. Crohn2357

    Mitochondrial impairment drives intestinal stem cell transition into dysfunctional Paneth cells predicting Crohn’s disease recurrence

    Mitochondrial impairment drives intestinal stem cell transition into dysfunctional Paneth cells predicting Crohn’s disease recurrence Sevana Khaloian1, Eva Rath1, Nassim Hammoudi2, Elisabeth Gleisinger1, Andreas Blutke3, Pieter Giesbertz4, Emanuel Berger1, Amira Metwaly1, Nadine Waldschmitt1...
  7. Crohn2357

    Incidence and prevalence of inflammatory bowel disease in UK primary care: a population-based cohort study

    Thomas Joshua Pasvol1, Laura Horsfall1, Stuart Bloom2, Anthony Walter Segal3, Caroline Sabin4,5, Nigel Field4,6, Greta Rait1,5 Received 27 December 2019 Revised 20 May 2020 Accepted 05 June 2020 Abstract Objectives We describe temporal trends in the recorded incidence of inflammatory bowel...
  8. Crohn2357

    Systematic review: gastrointestinal infection and incident inflammatory bowel disease

    Aliment Pharmacol Ther. 2020 Jun;51(12):1222-1232. doi: 10.1111/apt.15770. 2020 May 5. Systematic review: gastrointestinal infection and incident inflammatory bowel disease Jordan E Axelrad 1 , Ken H Cadwell 1 2 , Jean-Frederic Colombel 3 , Shailja C Shah 4 PMID: 32372471 PMCID...
  9. Crohn2357

    Serum Biomarkers Identify Patients Who Will Develop Inflammatory Bowel Diseases Up to 5 Years Before Diagnosis

    Serum Biomarkers Identify Patients Who Will Develop Inflammatory Bowel Diseases Up to 5 Years Before Diagnosis Joana Torres ∗ Francesca Petralia ∗ Takahiro Sato Mark S. Riddle § Jean-Frederic Colombel § on behalf ofthe Mount Sinai Road to Prevention Group Published: March 09, 2020 DOI...
  10. Crohn2357

    Effects of vitamin D supplementation on intestinal permeability, cathelicidin and disease markers in Crohn’s disease: Results from a randomised double

    United European Gastroenterol J. 2015 Jun; 3(3): 294–302. doi: 10.1177/2050640615572176 PMCID: PMC4480538 PMID: 26137304 Effects of vitamin D supplementation on intestinal permeability, cathelicidin and disease markers in Crohn’s disease: Results from a randomised double-blind placebo-controlled...
  11. Crohn2357

    New Drug - Mirikizumab

    https://www.pmlive.com/pharma_news/latecomer_lilly_preps_its_il-23_drug_for_crohns_disease_1288959?SQ_DESIGN_name=2&
  12. Crohn2357

    Comparative Effectiveness and Safety of Anti-Tumor Necrosis Factor Agents in Biologic-Naïve Patients with Crohn’s Disease

    Clin Gastroenterol Hepatol. Author manuscript; available in PMC 2017 Aug 1. Published in final edited form as: Clin Gastroenterol Hepatol. 2016 Aug; 14(8): 1120–1129.e6. Published online 2016 Apr 4. doi: 10.1016/j.cgh.2016.03.038 PMCID: PMC4955682 NIHMSID: NIHMS776209 PMID: 27058635...
  13. Crohn2357

    Using Stem Cells To Treat Perianal Fistulas

    https://www.ncbi.nlm.nih.gov/pubmed/31049792 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212615/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107517/ https://www.ncbi.nlm.nih.gov/pubmed/29578916 https://www.ncbi.nlm.nih.gov/pubmed/30772343...
  14. Crohn2357

    The IBD Therapeutic Pipeline is Primed to Produce

    Comprehensive. http://www.practicalgastro-digital.com/practicalgastro/april_2019/MobilePagedArticle.action?articleId=1495927#articleId1495927
  15. Crohn2357

    "What happens when you have a colonoscopy?"

    I found this short clip interesting. http://www.crohnsmapvaccine.com/what-happens-when-you-have-a-colonoscopy/
  16. Crohn2357

    Is Entyvio Effective At Treating Crohn's Flares?

    Is it effective at treating Crohn's flare-ups? I know it has been found to be effective for UC flare-ups, what about Crohn's? From what I have read and from my own experience with it, I find its effectiveness for treating moderate to severe Crohn's questionable
  17. Crohn2357

    (Podcast) Pioneering Researcher Alessio Fasano on Gluten, Autoimmunity & Leaky Gut

    https://kresserinstitute.com/rhr-pioneering-researcher-alessio-fasano-m-d-gluten-autoimmunity-leaky-gut/ https://en.wikipedia.org/wiki/Zonulin https://en.wikipedia.org/wiki/Alessio_Fasano Zonulin, regulation of tight junctions, and autoimmune diseases Zonulin and Its Regulation of...
  18. Crohn2357

    Questions for people who had a total colectomy or a proctocolectomy

    Hi, I have a few questions. How many bowel movements do you have in a day, generally (if you have a pelvic pouch)? Could you describe the stool consistency? Do you suffer from dehydration more easily than the general population, because of the lack of colon? How is your blood pressure...
  19. Crohn2357

    Swedish Bitters For Crohn's/UC?

    Has anyone tried Swedish Bitters for Crohn's/UC? Does it help?
  20. Crohn2357

    Swedish Bitters For Crohn's/UC?

    Has anyone tried Swedish Bitters for Crohn's/UC? Does it help?
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