• Welcome to Crohn's Forum, a support group for people with all forms of IBD. While this community is not a substitute for doctor's advice and we cannot treat or diagnose, we find being able to communicate with others who have IBD is invaluable as we navigate our struggles and celebrate our successes. We invite you to join us.

Search results

  1. Scipio

    Zeposia (Ozanimod) Flunks Its Crohn's Clinical Trial

    Bad News: Zeposia, which is already approved by the FDA for treating multiple sclerosis and ulcerative colitis, failed to hit its target endpoint in its Phase III clinical trial of Crohn's disease...
  2. Scipio

    History of IBD Linked to Severe Outcomes in Patients Hospitalized for COVID

    Keep those masks handy and vaccines up to date: https://www.medpagetoday.com/meetingcoverage/ccc/108524
  3. Scipio

    Higher Vitamin D Levels are Associated with Improved Outcomes in IBD Patients Treated with Entyvio

    https://www.mdpi.com/2072-6643/15/22/4847 From the paper: Conclusions Our retrospective study of patients on vedolizumab therapy for both UC and CD found that higher pre-treatment vitamin D levels were associated with higher endoscopic improvement in UC and greater nutritional and...
  4. Scipio

    New 5-minute Blood Tests for Remicade and Humira Have Been FDA Approved

    https://www.fiercebiotech.com/medtech/fda-greenlights-5-minute-tests-track-humira-remicade-doses-patients-inflammatory-bowel
  5. Scipio

    Entyvio Receives FDA Approval for Injectable Version

    Until now Entyvio has been by infusion only in the US: https://www.fiercepharma.com/pharma/takedas-scores-second-chance-subcutaneous-version-entyvio
  6. Scipio

    Skyrizi Beats Stelara in Several Key Factors in Head-to-Head Comparison Trial

    https://www.prnewswire.com/news-releases/abbvies-skyrizi-risankizumab-met-all-primary-and-secondary-endpoints-versus-stelara-ustekinumab-in-head-to-head-study-in-crohns-disease-301924034.html
  7. Scipio

    Scientists Get a Better Understanding of How Stress Can Inflame the Gut in IBD Patients

    " Psychological stress is known to worsen the gut inflammation caused by certain bowel diseases. Now scientists have found out why. New research1 outlines a sweeping narrative that begins with chemical cues produced in the brain and ends with immune cells in the gut — a sequence that spells...
  8. Scipio

    First JAK Inhibitor Approved by FDA for Treatment of Crohn's

    Rinvoq: https://www.medpagetoday.com/gastroenterology/inflammatoryboweldisease/104570?xid=nl_mpt_DHE_2023-05-18&eun=g1228878d0r&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%20Evening%202023-05-18&utm_term=NL_Daily_DHE_dual-gmail-definition A new class of drugs for...
  9. Scipio

    Understanding of the Genetic Basis of IBD Susceptibility Increases with Addition of East Asian Patients

    Article https://www.genomeweb.com/microarrays-multiplexing/inflammatory-bowel-disease-genetics-understanding-expands-east-asian?utm_source=Sailthru&utm_medium=email&utm_campaign=GWDN%20Mon%20PM%202023-05-08&utm_term=GW%20Daily%20News%20Bulletin#.ZFlZ33bMKUk The paper...
  10. Scipio

    Antibiotic Use Associated with Increased Risk of IBD

    New study: https://gut.bmj.com/content/early/2023/01/03/gutjnl-2022-327845 "Conclusion Antibiotic exposure is associated with an increased risk of IBD, and was highest among individuals aged 40 years and older. This risk increased with cumulative antibiotic exposure, with antibiotics targeting...
  11. Scipio

    Receptor on Gut Cells is Also Present on Immune Response Cells

    This is very early basic research, but finding the same receptor protein on the surface of both gut and immune cells opens a new approach to treating/curing IBD. This is years or decades away from clinical use, but it is encouraging to see new approaches opening up...
  12. Scipio

    Preventing IBD May Not be Hopeless

    From the article: "Adopting and maintaining a healthy lifestyle may prevent inflammatory bowel disease (IBD), according to findings from an analysis of three prospective U.S. cohort studies, which were validated in three external European cohorts. In the primary analysis, maintaining low...
  13. Scipio

    Reassuring data on NSAIDs in IBD flares

    https://www.mdedge.com/gihepnews/article/257658/gastroenterology/reassuring-data-nsaids-ibd-flares?ecd=WNLPD_GIHEP_221026_mdedge
  14. Scipio

    Phage Cocktail Holds Promise for IBD

    Phages are viruses that infect and kill bacteria. The full name of this type of virus is “bacteriophage.” Phage is the Greek word φαγε written in Latin letters and means “to eat.” So a bacteriophage is literally a “bacteria eater.” Since their discovery in the first half of the 20th century...
  15. Scipio

    Funding Bill with AGA Language on IBD Heads to the House Floor

    A bill from the Appropriations Committee that includes the committee’s support for NIH to fund basic, translational, and clinical studies on the diagnosis and treatment of IBD is headed for vote from the full House of Representatives...
  16. Scipio

    Skyrizi (anti-IL23 antibody) Approved for Treatment of Crohn's Disease

    Another new option for treating Crohn's. https://www.prnewswire.com/news-releases/skyrizi-risankizumab-rzaa-receives-fda-approval-as-the-first-and-only-specific-interleukin-23-il-23-to-treat-moderately-to-severely-active-crohns-disease-in-adults-301570300.html It probably will be similar to...
  17. Scipio

    Stelara and Humira Show Similar Effectiveness in Crohn's Remission Induction and Maintenance

    In a head-to-head comparison trial there were no significant differences between how well the two drugs worked: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00688-2/fulltext This is slightly surprising to me, since the two drugs work by different mechanisms, and the...
  18. Scipio

    Having a Dog (but not a cat) When Young is Associated with Lower Risk of IBD

    From DDW: https://ddw.org/2022/05/23/living-with-dogs-but-not-cats-as-a-toddler-might-protect-against-crohns-disease/
  19. Scipio

    Stelara and Entyvio Associated with Lower Risk of Serious Infections in Older IBD Patients Compared to Anti-TNFs

    From DDW: https://www.healio.com/news/gastroenterology/20220531/vedolizumab-ustekinumab-best-antitnf-for-infection-risk-in-older-adult-ibd
  20. Scipio

    Promising Phase III Clinical Trial Results for JAK Inhibitor for Crohn's Reported

    Rinvoq therapy for maintenence treatment of moderate to severe Crohn's. This is the type of data that usually leads to FDA approval...
Top