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  1. kiny

    Specific pathobionts are enriched during flares in patients with severe CD

    Specific gut pathobionts escape antibody coating and are enriched during flares in patients with severe Crohn’s disease 2024 Feb 23 Department of Biotechnology and Biomedicine, Technical University of Denmark Objective Patients with Crohn’s disease (CD) exhibit great heterogeneity in...
  2. kiny

    1973. Intravenous alimentation.

    1973-1977 discussion on use of Intravenous alimention (bowel rest) in crohn's disease for nutritional support. Subsequent realisation it induces remission in patients with Crohn's disease, but not UC. Crohn's Disease was referred to as Regional Enteritis back then. DR. FRANCIS C. NANCE (New...
  3. kiny

    Amount and fate of egg protein escaping assimilation in the small intestine of humans.

    Amount and fate of egg protein escaping assimilation in the small intestine of humans 1999 P Evenepoel, D Claus, B Geypens, M Hiele, K Geboes, P Rutgeerts, Y Ghoos University Leuven, Belgium The availability of stable isotope-labeled protein allowed us to determine the amount and fate of...
  4. kiny

    Intestinal Th17 Subset is Associated with Inflammation in Crohn’s Disease and Activated by AIEC

    1654×2174 365,8 kB
  5. kiny

    The Crohn’s Disease Exclusion Diet (CDED): A Comprehensive Review

    I think the positive data for CDED has been weak so far. While CDED is more restrictive, previous studies where a 50% EN and 50% free diet was tried failed. Still, the idea of only having to consume 50% EN combined with a less restrictive diet is appealing to increase compliance with patients...
  6. kiny

    From ASCA breakthrough in Crohn's disease and Candida albicans research to thirty years of investigations about their meaning in human health

  7. kiny

    Bacterial and fungal microbiome of children with Crohn’s and the modifying effects of EN.

    -fungal communities differed between healthy children and those with CD -faecal samples showed EN caused dramatic changes in fungal communities and diversity, more so than in bacterial communities -fungus S. cerevisiae (ASCA yeast) significantly decreased during EEN -subjects with lower...
  8. kiny

    Daily consumption of fruit/vegetables in OECD countries and crohn's disease prevalence.

    Lack of fruits/vegetables and specifically the subsequent association with lack of fiber intake is often blamed on the increasing prevalence of crohn's disease. Especially after a study a few years ago came out suggesting lack of fiber intake was associated with later development of crohn's...
  9. kiny

    Reduction faecal calprotectin during EN is lost rapidly after food re‐introduction

    -EN shows largest decrease in calprotectin at 4 weeks -EN continues to decrease calprotectin at 8 weeks but at a slower rate -Results show EN effectiveness might be dose-dependent (a similar study in Japan also suggested this) -discontinuation of EN increases calprotectin within 17 days...
  10. kiny

    Fiber-deficient diet inhibits colitis through the regulation of the niche and metabolism of a gut pathobiont

    Fiber-deficient diet inhibits colitis through the regulation of the niche and metabolism of a gut pathobiont 14 November 2023 Department of Microbiology and Immunology, University of Michigan Department of Public Health and Preventive Medicine, Yamaguchi University, Japan Peter Kuffa, Joseph...
  11. kiny

    Intestinal fungal commensals and food-derived yeasts, drives inflammatory CD4+ T cell responses in patients with CD

    Nature Medicine University Medical Center Schleswig-Holstein, Kiel, Germany Cornell University, NY, USA 25 of september 2023
  12. kiny

    Presence of maltodextrin, emulsifiers or lack of fibre do not impact effectivness of EN.

    All the studies that scare people regarding emulsifiers, polysorbate 80, maltodextrin, and tell people to eat more fibre, based on their studies in petri dishes, need to start explaining how EN full of emulsifiers, maltodextrin, and complete lacking in fibre are the most effective treatment for...
  13. kiny

    Are fungi found in the stool actually present in the intestine.

    It seems like an odd question. By asking this you are challeging the notion of a gut mycobiome consisting of fungi. Most studies naturally assume that when fungi like Candida spp and Malassezia are found in stool of patients with crohn's disease, that they have colonized the gut where they...
  14. kiny

    The overwhelming evidence linking acute infections to crohn's disease onset.

  15. kiny

    Intestinal epithelial autophagy is essential for host defense against invasive bacteria

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  16. kiny

    Antimicrobial Susceptibility Testing for Three Malassezia Species

  17. kiny

    CRP in Outpatients with Inflammatory Bowel Disease Is Linked to the Blood Microbiota

  18. kiny

    Changes in the gut mycobiome in pediatric patients in relation to the clinical activity of Crohn's disease

  19. kiny

    Food antigen-induced immune responses in Crohn’s disease patients and experimental colitis

    One of the few studies that did a wide antibodies presence study on common foods in patients with Crohn's disease. It shows a very high IgG response against buckwheat, corn, oat, pecan, cabbage, lettuce, celery, rice, onion, spinach, tomatoes, grapefruits and yeasts. The antibody response is...
  20. kiny

    The very high level of clustering of Crohn's Disease.

    Van Kruiningen his old studies showed the fact Crohn's Disease features high level of clustering in Northern France and Belgium. It is only when you look at recent detailed maps when you start to appreciate the level of clustering. There is a major environmental factor involved in crohn's...
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