Crohn's Disease Forum » Books, Multimedia, Research & News » Prevalence and correlates of vitamin K deficiency in children with inflammatory bowel disease


06-23-2018, 11:47 PM   #1
Crohn2357
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Prevalence and correlates of vitamin K deficiency in children with inflammatory bowel disease

Sci Rep. 2014 Apr 24;4:4768. doi: 10.1038/srep04768.
Prevalence and correlates of vitamin K deficiency in children with inflammatory bowel disease.
Nowak JK1, Grzybowska-Chlebowczyk U2, Landowski P3, Szaflarska-Poplawska A4, Klincewicz B1, Adamczak D5, Banasiewicz T6, Plawski A7, Walkowiak J1.

Abstract

Although vitamin K deficiency has been implicated in adult inflammatory bowel disease (IBD), its prevalence in pediatric IBD remains unknown. We carried out a cross-sectional study in 63 children with Crohn's disease (CD) and 48 with ulcerative colitis (UC) to assess the prevalence of vitamin K deficiency and to search for potential correlation between vitamin K status and pediatric IBD activity. Vitamin K status was assessed using protein induced by vitamin K absence-II (PIVKA-II; ELISA). Prevalence of vitamin K deficiency was 54.0% in CD and 43.7% in UC. Vitamin K deficiency was more common in patients with higher CD activity, in CD patients with higher mass Z-scores, and less common among children with CD treated with infliximab. Relation of vitamin K deficiency to pediatric IBD clinical course and treatment demand further research.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998013/
06-25-2018, 10:36 AM   #2
Scipio
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06-25-2018, 10:58 AM   #3
my little penguin
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Most kids with crohns have difficulty eating vegetables (raw or slightly cooked )
Especially leafy veggies (not because they donít like them )
They come out how they went in. No absorption
Which can lead to multiple vitamin deficiency
That said
Most Crohns kids are placed on formula (semi elemental or elemental) as a supplement to avoid those issues until growth is complete
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