David
Co-Founder
- Location
- Naples, Florida
I'm curious how many of you have had your fecal calprotectin or CRP levels tested?
Thanks
Thanks
I'm curious how many of you have had your fecal calprotectin or CRP levels tested?
Thanks
Background
Research has shown that fecal biomarkers are useful to assess the activity of inflammatory bowel disease (IBD). The aim of the study is: to evaluate the efficacy of the fecal lactoferrin and calprotectin as indicators of inflammatory activity.
Findings
A total of 78 patients presenting inflammatory bowel disease were evaluated. Blood tests, the Crohn's Disease Activity Index (CDAI), Mayo Disease Activity Index (MDAI), and Crohn's Disease Endoscopic Index of Severity (CDEIS) were used for the clinical and endoscopic evaluation. Two tests were performed on the fecal samples, to check the levels of calprotectin and lactoferrin. The performance of these fecal markers for detection of inflammation with reference to endoscopic and histological inflammatory activity was assessed and calculated sensitivity, specificity, accuracy.
A total of 52 patient's samples whose histological evaluations showed inflammation, 49 were lactoferrin-positive, and 40 were calprotectin-positive (p = 0.000). Lactoferrin and calprotectin findings correlated with C-reactive protein in both the CD and UC groups (p = 0.006; p = 0.000), with CDAI values (p = 0.043; 0.010), CDEIS values in DC cases (p = 0,000; 0.000), and with MDAI values in UC cases (p = 0.000).
Conclusion
Fecal lactoferrin and calprotectin are highly sensitive and specific markers for detecting intestinal inflammation. Levels of fecal calprotectin have a proportional correlation to the degree of inflammation of the intestinal mucosa.
Uveitis is an EIM(extra instestinal manifestation) of Crohn's Disease. I have read several threads on here of members that are dealing with Hashimotos and CD. As for alopecia and CD I did find this article(<---click here), that states there may be a correlation between the two.
You may want to utilize the forum search option at the top of the page to bring up relevant threads, a keyword search of alopecia or hashimotos should bring up the threads posted by other members.
Glad you got a dx. A few people on the forum did theirs as they came out of a flare up. My GI wanted mine done during a flare up, as they did yours too.Had mine tested last year when went to GP with persistent diarrhoea- result 940.
Colonoscopy followed 3 months later which gave me my diagnosis of lymphocytic colitis.
Indeed the WBC was above limits, and the Hb was below limits, only just. The HS CRP units are not mentioned. If in mg/l, this is elevated:Thanks smt.
WBC-12.9
Hgb- 109
Serum Iron-5.0
% Iron Sat- 10.5
hsCRP- 9.0
My daughter just had hers tested came back 2500. normal is <50 . doctor ordered colonoscopy and upper scope. Upper is healthy but She has ulcerative colitis.I'm curious how many of you have had your fecal calprotectin or CRP levels tested?
Thanks
I'm have a silly question for everyone who has done the fecal calprotectin; What did you carry the "sample" in? My last one was done on a very hot day. The doctor said to keep it cold and we live 45 minutes away from my GI. I didn’t want fecal matter in any reusable cooler so I put the sample in the given container then put that in an empty Folger can that I'd put ice in. You should have seen the Gosh awful look the phlebotomy/ lab girl gave me. LOL! It was great. She gasped and said I don't think I can take THAT. I said relax I'm sick not stupid. Hahaha.I'm curious how many of you have had your fecal calprotectin or CRP levels tested?
Thanks
Good idea to see the head doctor. Is this a Gastroenterologist?My C-Reactive Protein is 181, it's supposed to be 8 and my PA says she is worried and I am seeing the head doctor.