Recommendations:
Store biologics at 2-8 ºC; when taken out of the refrigerator should be kept at room temperature less than 25ºC
Studies have shown that etanercept may be safely stored at room temperature conditions of 25°C±2°C (77°F) for up to 1 month
https://t.co/HMf7pcVudE
I advise patients who are traveling to either: A) take their biologic a few days earlier or later to avoid traveling with drug; or B) if they travel with a biologic they keep it cool, dark and dry. Remove from the refrigerator, wrap the injectable syringe in bubble wrap or light insulation (no need for an ice chest or dry ice), put it in a purse or briefcase and bring the box label. The syringe is safe on planes & hotels as long as they are at room temperature, away from sunlight or heat.
http://rheumnow.com/blog/tips-arthritis-travelers-best-2015-3
Discard drugs that have been frozen or improperly storage (call pharmacy or manufacturer for a replacement)
Pharmacists and nurses must counsel patients on the importance of storage conditions
There are companies developing apps to monitor drug temperature and usability.
https://buff.ly/2rsHJ5v
Manufacturers should develop and incorporate temperature-sensitive warning devices that can be incorporated into packaging.
Tell patients to avoid storing Biologics in lower CRISPER Drawers, were the temperature is always lower (usually below 2°C or below 36° F). The lower temperature in the Crisper is optimal for storing produce and meats.