Crohn's Disease Forum » Treatment » Low Dose Naltrexone » Question about contrave

10-22-2015, 01:19 PM   #1
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Question about contrave

My primary ia putting me on contrave for weight loss/depression. Its bupropion and naltrexone.

Wondering if anyone knows how this compares to a LDN regimen that others have seen help their crohns?
10-28-2015, 08:50 AM   #2
Join Date: Feb 2012
Location: Providence, Rhode Island

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Hi Aideen, sorry that I didn't see this until now. I'm not an expert, so take this with a grain of salt, but the typical agreed-upon dosage amount for LDN is 4.5mg, once per day. I took a quick look at the Contrave website, and it looks like the naltrexone is an 8mg dose in an extended-release capsule format. That's certainly a lower dose than normal naltrexone (standard doses for generic naltrexone HCl are 50mg pills), but I'm not sure whether 8mg would have the same effects as traditional LDN.

My guess: I don't think that it will hurt anything, but I don't know that it will have a tangible effect on your Crohn's.

Hopefully someone else can chime in that has a little bit more knowledge on the subject.
Hi, I'm Jesse!

Current meds:
Inflectra (5mg/kg)
fluoxetine (20mg)

Previous meds:
Dexilant (too pricey!), Xifaxan (short course), budesonide (tapered off), prednisone (fun!), Pentasa (had to switch in January 2016), Lialda, generic mesalamine, omeprazole, LDN

2000IU vitamin D-3

gastritis & duodenal ulcers, August 2011
Mild Crohn's in terminal ileum, February 2012
5cm of narrowing w/ no signs of active inflammation, May 2014

Crohn's Disease Forum » Treatment » Low Dose Naltrexone » Question about contrave
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