I am on my 1 year remiversary. I get my official 1 year infusion on friday. So far so good. The only real side effect I have had is some non crohns related severe abdominal pain. It hasnt happened in a few months. When it did happen it would last about a day, and it only hit me every month give or take a couple weeks. The last 2 infusions I had some minor joint pain for a day or 2 after, but it always resolves itself. Other than that I am enjoying complete remission. I get 3 vials every 7 weeks.