I've been on 6mp 100 mg for 20 years and am having major skin problems and just landed in the hospital for the first time with a partial blockage. Went to the GI and he said it's time to switch meds. I'm so nervous. I'm sure that 6mp has just has many potential complications as Entyvio. I just feel so comfortable on the 6mp because my labs have always been normal and i've lived a fairly normal life. We are waiting on insurance approval and then we are moving forward. YIKES! Any positive responses are welcome. Have you switched from 6mp to Entyvio with success?