I have been on Remicade for about three years. I also did a short cycle about 10 years ago. I started off getting it every 8 weeks, now I receive the IV every four weeks with a really large dose or so the nurses say, I know my Dr. raised it when I went to four weeks.
I never noticed weight gain outside of just feeling better and eating more. Now that I am not responding as well I have only had about 2-3 lbs of weight gain since January.
The most noticeable side effects for me are fatigue. It really wears me down. I also get some head aches the week of. Most side effects seem to diminish as the weeks pass.
When Remicade is working it is a wonderful drug, always picked me right up. One of the worst things outside of side effects is the cost, never knew an IV could be so expensive until I started Remicade.