I have history of antibiotics for rosacea. I'm sure my gut was severely out of whack...thus the Crohns? My physician recommended Align and Myralax (chronic constiptation), B12 shots and I felt like a million dollars for several months. Then of course, all the testing and preps I think aggravated my stricture issues resulting in surgery. But I give a big thumbs up on Align. One of those 2 was causing me gas blow initially however no pain...I think the Align? I think it was just regulating the bowel because it discontinued greatly.