I've been on Mercaptopure (6MP) for quite a while now, and it works pretty well for me. For the past few months, my liver tests haven't been good, and my ALT and AST have been elevated. My most recent test results were so high my doctor is cutting my dosage. This is the exact same scenario that happened 3 years ago that led to a year long flare. I am trying hard to stay optimistic but it isn't always easy.