My son (14) has been diagnosed with Crohn's 5 years ago. His initial Calprotectin levels were between 2000 and 3000. After a year and a half of Prednisone, Salazopyrin and Entocort his levels shot up to over 6000 (literally off the chart). The doctor ordered another test assuming that it was a false positive but the result was the same. My son started Humira and his levels was the lowest at 2500 before it shot up to >6000 again. Then he was switched over to Stelara and his levels came down to about 5000 after 6 months. It went back to >6000 again and he is going to start Entyvio as soon as we get approval from the insurance. What I actually want to know is if there is anyone who had Calprotectin levels this high. My son has been to 3 doctors - none of them can explain this ridiculous high result. His latest test is the 5th test with a number >6000 - it cannot be all false positives. I would also like to mention that I do use a sterile container and I take the stool sample immediately to the labs.