From what I know it just measures inflammation that is currently present, it can’t say if the inflammation is chronic. 290 while high isn’t anything crazy and could definitely be explained by document rectal inflammation. When I was diagnosed with UC my calprotection was well above 1000 though I was never given an exact number. When my levels were rechecked after I started prednisone it was 83. I would like to clarify this is just as I understand it, and my experience.