• Welcome to Crohn's Forum, a support group for people with all forms of IBD. While this community is not a substitute for doctor's advice and we cannot treat or diagnose, we find being able to communicate with others who have IBD is invaluable as we navigate our struggles and celebrate our successes. We invite you to join us.

Canadian medical research breakthrough - Gut bacteria combination shows risk for Crohn's disease

J

J100

wildbill_52280

wildbill_52280

I like this! Although they might be overselling it a bit when they said something like its the only project that matters and so forth. then one page says they are tracking bacteria and another says they are using blood samples, kinda weird. Also it says they study started in 2008, that was 15 years ago!!
 
J

J100

It is possible that they may be overselling it. As I have said, this by itself has to lead to a successful clinical trials of newer medications. I think the reason it took so long was because they actually monitored healthy relatives along with the people who had Crohn's or went on to develop Crohn's.
Canada has had a good record in research. There are newer ways being worked upon to balance the gut microbiome. Let's hope for the best. That's all we can do.
 
W

wduk

J100 said:
www.newswire.ca

Canadian medical research breakthrough - Gut bacteria combination shows risk for Crohn's disease

/CNW/ - A Canadian research team has discovered that the gut bacteria combination of those who go on to develop Crohn's disease is different from those who...
www.newswire.ca www.newswire.ca

I watched the youtube video and they claim that this is ground breaking. Let's hope it can result in newer treatments which are safer with potentially less adverse impacts.
Click to expand...
Am I blind or did the article not mention which bacteria have been identified as possible problem combinations?
 
A

asadmom

wduk said:
Am I blind or did the article not mention which bacteria have been identified as possible problem combinations?
Click to expand...
You are not blind. That is the first question I thought of when I read the article. To start - disclose the list of the offending bacteria. Put people on EEN and observe the population of the bacteria in all the people. Then, we talk.
 
W

wduk

asadmom said:
You are not blind. That is the first question I thought of when I read the article. To start - disclose the list of the offending bacteria. Put people on EEN and observe the population of the bacteria in all the people. Then, we talk.
Click to expand...
I did some digging and found the data:


Results
In the validation cohort, the microbiome risk score (MRS) model yielded a hazard ratio of 2.24 (95% confidence interval, 1.03-4.84; P = .04), using the median of the MRS from the discovery cohort as the threshold. The MRS demonstrated a temporal validity by capturing individuals that developed CD up to 5 years before disease onset (area under the curve > 0.65). The 5 most important taxa contributing to the MRS included Ruminococcus torques, Blautia, Colidextribacter, an uncultured genus-level group from Oscillospiraceae, and Roseburia.

www.sciencedirect.com

Gut Microbiome Composition Is Associated With Future Onset of Crohn’s Disease in Healthy First-Degree Relatives

The cause of Crohn’s disease (CD) is unknown, but the current hypothesis is that microbial or environmental factors induce gut inflammation in genetic…
www.sciencedirect.com www.sciencedirect.com
 
You must log in or register to reply here.
Top