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Cimzia vs Humira
- Thread starter silveyk
- Start date
Crohn's Mom
Moderator
My daughter actually just had her first loading dose of Cimzia today. It was relatively uneventful, so that is a good thing in my mind.
The only thing we noticed today is that about an hour or so after the injections she got really tired, and then slept for about 3 hours.
Just want to wish your Wife the best of luck !
Our GI refers to Cimzia as the "bad ass new one that puts the other 2 to shame!"
We shall see I guess
The only thing we noticed today is that about an hour or so after the injections she got really tired, and then slept for about 3 hours.
Just want to wish your Wife the best of luck !
Our GI refers to Cimzia as the "bad ass new one that puts the other 2 to shame!"
We shall see I guess
You might want to check out the CImzia Club topic, or just do a search for Cimzia. There's not a ton of us on it, but there is some info out there that may help you. Best of luck, hope Cimzia is the answer for her!
To answer your question, it worked for me for almost a year and it was GREAT. Then it lost its efficacy. We then added 6MP and Pred. That also kind of worked. I'm now trying to decide on whether or not I want to join a clinical trial for an Interleukin (IL6)drug or continue with these meds that are only "kind of" working. But when Cimzia worked for me, it REALLY worked. For awhile I almost forgot I had Crohn's. I hope it works as well and much, much longer for your wife.
To answer your question, it worked for me for almost a year and it was GREAT. Then it lost its efficacy. We then added 6MP and Pred. That also kind of worked. I'm now trying to decide on whether or not I want to join a clinical trial for an Interleukin (IL6)drug or continue with these meds that are only "kind of" working. But when Cimzia worked for me, it REALLY worked. For awhile I almost forgot I had Crohn's. I hope it works as well and much, much longer for your wife.
I was on Remicade then Humira and Cimzia just before my surgery. I don't think I was able to give it a chance before my surgery as my strictures were so bad. So my doc wants me to start it again. I am reluctant as the others mentioned worked in the beginning then either had terrible side effects (blurred vision, etc) that I don't really have a lot of faith! BUT the surgery didn't work either so here we go!My daughter actually just had her first loading dose of Cimzia today. It was relatively uneventful, so that is a good thing in my mind.
The only thing we noticed today is that about an hour or so after the injections she got really tired, and then slept for about 3 hours.
Just want to wish your Wife the best of luck !
Our GI refers to Cimzia as the "bad ass new one that puts the other 2 to shame!"
We shall see I guess
The difference between Humira and cimzia is:
1 Humira is an intact monoclonal Ab vs TnF. It lasts 2 weeks.
2 Cimzia is an mAb fragment attached to polyethylene glycol to make it last longer in the body.
However, the quantity of protein used for the two drugs is greatly different.
120 mg loading dose for humira vs 400 mg loading dose for cimzia. Subsequent doses of Cimzia are still quite higher than for humira.
The large amount of protein injected can cause loss of efficacy that some have reported in this forum and side effects, ie sleepiness. Also with Cimzia you can develop antibodies to both the protein Cimzia and the PEG.
1 Humira is an intact monoclonal Ab vs TnF. It lasts 2 weeks.
2 Cimzia is an mAb fragment attached to polyethylene glycol to make it last longer in the body.
However, the quantity of protein used for the two drugs is greatly different.
120 mg loading dose for humira vs 400 mg loading dose for cimzia. Subsequent doses of Cimzia are still quite higher than for humira.
The large amount of protein injected can cause loss of efficacy that some have reported in this forum and side effects, ie sleepiness. Also with Cimzia you can develop antibodies to both the protein Cimzia and the PEG.