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CNN - fecal transplant for c. diff

Another story in the news about fecal transplants for curing c. diff. This patient was in a car accident and developed c. diff from all the antibiotic use. They tried the nasogastric route but the infection came back. Then, they tried the implant again with a colonoscopy and had excellent results.

Little-known fecal transplant cures woman's bacterial infection

From the article:

Increasingly, doctors are taking a different approach. Instead of continued assaults on bacteria, "fecal matter transplants" recolonize the colon with new bacteria from a healthy donor.

"This is brand-new for most gastroenterologists," said Dr. Suku George, Hunter's treating physician. "We are very excited about this."

George had never deposited fecal matter by colonoscopy into a patient until Hunter wanted to try it.

Hunter's mother "donated" one of her stools for the procedure. Next, the hospital lab carefully diluted it, and George pumped the foreign fecal matter right into Hunter's colon.

The result ended Hunter's struggle with C. diff.

A study published in March reported a 91% cure rate after just one fecal matter transplant, and a 98% cure rate when combined with an additional round of antibiotics.

Remarkably, that study only included the sickest of patients. All 77 of the study participants already had a recurring C. diff infection, having tried and failed five rounds of antibiotic-only treatments over 11 months, on average.

The study used the colonoscopy method, which many believe is the most effective, because relatively large amounts of fecal matter can be placed deep inside the colon.

Other methods use either an enema or a nasogastric tube, which sends fecal matter through the nasal passage, down the throat and into the stomach.

George tried the nasogastric tube on Hunter, using fecal material from her father, but the C. diff infection returned. He then asked for and received permission to perform the hospital's first colonoscopic fecal transplant.
 
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