I have been through all of the loading doses of Entyvio and am now on the 8-week schedule. Prior to starting Entyvio, I was without medication for about 2.5 months (waiting for its FDA approval). Since being off medication, instead of frequent trips to the bathroom, I am rarely going at all. I have to take Miralax each morning and it is still a struggle and what comes out isn't formed. In addition to that, I'm feeling "pressure" in my lower right quadrant of my abdomen which is where I had surgery 3 years ago. My concern is that I may be getting another stricture. I am not due for a colonoscopy until mid-next year and my doctor is holding to that timeframe. I asked if we could move it up because I really don't feel right. No luck. My question is, should I persist and ask my doctor again to move my colonoscopy up? Or should I just relax and follow the doctor's plan?