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Covid vaccine antibody Home game for ibd

my little penguin

Staff member
For those curious
Of 2499 health care workers who received 2 doses of SARS-CoV-2 mRNA vaccines, 1647 participated in this study. A total of 688 were vaccinated with mRNA-1273 (mean age, 43.2 years; 76.7% women; 21.8% previously infected with SARS-CoV-2), and 959 with BNT162b2 (mean age, 44.7 years; 84.9% women; 13.2% previously infected).

Higher antibody titers were observed in participants vaccinated with 2 doses of mRNA-1273 compared with those vaccinated with BNT162b2 (geometric mean titer [GMT], 3836 U/mL [95% CI, 3586-4104] vs 1444 U/mL [95% CI, 1350-1544]; P < .001) (Figure, A).

Previously infected participants had higher antibody titers (GMT, 9461 U/mL [95% CI, 8494-10 539]) compared with previously uninfected participants (GMT, 1613 U/mL [95% CI, 1539-1690]) (P < .001). In both groups, those vaccinated with mRNA-1273 had higher antibody titers compared with those vaccinated with BNT162b2 (previously uninfected: GMT, 2881 U/mL [95% CI, 2721-3051] vs 1108 U/mL [95% CI, 1049-1170]; P < .001; previously infected: GMT, 10 708 U/mL [95% CI, 9311-12 315] vs 8174 U/mL [95% CI, 6923-9649]; P = .01). The difference in antibody levels according to previous infection was higher than the difference between the 2 mRNA vaccines (Figure, B, and Table).

those numbers are for folks with a normal immune system
After two shots
Moderna levels at 3836 U/ml
Pzfier levels at 1444

the nc study link here

conversion from NC study is 11.4 x mu/ml
To get U/ml
Ibd average after 3 shots

Was 132.5 mu/ml or 1510.5 U/ml
Which means most IBD patients despite meds were about the same after three doses as the average non ibd person after two shots

I call that a win
What is required for ibd patients is not known yet
But it gives me as a parent a more warm and fuzzy to know my ibd kiddo is at 1686 U/ml after three shots

hope it helps all those playing the home game version with their kids