A couple of things I got from this were the need for personalised treatments, and that dietary interventions (via interactions with bile acids) are likely to be much more impactful in small bowel Crohn's, and bacteria-centric therapies in colonic Crohn's (and UC). I already knew that diet was more important in Crohn's, and bacteria in UC, but of course Crohn's can affect the colon as well. So maybe colonic Crohn's can be treated similarly to UC.
I'd be interested to hear his thoughts on AIEC in particular, although I get the impression he would think they're not the whole story. At least, not in everyone.
Definitely enjoying the format of these videos. People are doing the science, but it's not always communicated very well, or very clearly. So we need more of this.