Do your doctors switch you off of a medication as soon as you've had a flare? My son flared for three days and then his symptoms went away. He has been on Entyvio for around 10 months, and up until now we thought it might be working because his numbers were good. However, his calprotectin level during the flare shot up to around 320. Does this mean it's not working and we need to switch to yet another medication?