I was diagnosed with Crohn's in Jan 2011 and it has been a bumpy road, but I am finally feeling a little more myself lately. I am tapering off my prednisone and I am on Imuran, which seems to be working. However, I have developed a fistula, with a hole in my butt cheek and they do not know what it is attached to. I had an MRI yesterday and will find out the results in two weeks. Most of you talk about the pain that comes with the fistula, but the only real pain for me if the opening in the skin and sitting on the area or my clothes rubbing on it. However, it does discharge small amounts of stool, and getting less and less everyday. Has anyone had one attached to their rectum and not provided much pain and is there a chance that it will close up on its own? I am also on Cipro and Flagyl until the fistula is sorted out.