Hello and almost merry Christmas to my fellow IBD'ers.
I am new to this site and forums, so please forgive me if the format isn't the norm.
I had undiagnosed crohns from the age of approx 17 years of age through to approximately age 32 when finally, a wonderful consultant diagnosed the disease.
To date I have had 17 surgeries for peri-anal fistula, colostomy/reversal and resection, not to mention the wonderul amount of colonoscopies.
I write today in hope of gaining some advice. I had a routine appointment in July of this year with my Consultant. I explained to him that 100mg of Azathioprine taking once daily on a morning was causing me to tremor. He advised me to reduce the dose to 50mg based on my condition having been stable for minimum of 4 years. Within 2 weeks of reducing the dose I was admitted to hospital in extreme pain and diagnosed from CT scan as having Crohns Flare of terminal ileum and narrowing. Metronidazole, Methyl Pred settled symptoms and discharged 10 days later with 40mg reducing dosage weekly. The prednisolone has ended and symptoms recurred. Consultant did colonoscopy to fund ulceration and the narrowing as mentioned previously. Restarted on Prednisolone at 40mg an advised to split azathioprine to 50mg am and 50mg evening. Again the pred came to an end and symtpoms all back again. Each time CRPs negatve but feacal calprotectin shows significant inflamation. Consultant due to see me in Jan to discuss Humira but why on earth is my CRP not raised? Any guidance is greatly appreciated. :yfaint:
I am new to this site and forums, so please forgive me if the format isn't the norm.
I had undiagnosed crohns from the age of approx 17 years of age through to approximately age 32 when finally, a wonderful consultant diagnosed the disease.
To date I have had 17 surgeries for peri-anal fistula, colostomy/reversal and resection, not to mention the wonderul amount of colonoscopies.
I write today in hope of gaining some advice. I had a routine appointment in July of this year with my Consultant. I explained to him that 100mg of Azathioprine taking once daily on a morning was causing me to tremor. He advised me to reduce the dose to 50mg based on my condition having been stable for minimum of 4 years. Within 2 weeks of reducing the dose I was admitted to hospital in extreme pain and diagnosed from CT scan as having Crohns Flare of terminal ileum and narrowing. Metronidazole, Methyl Pred settled symptoms and discharged 10 days later with 40mg reducing dosage weekly. The prednisolone has ended and symptoms recurred. Consultant did colonoscopy to fund ulceration and the narrowing as mentioned previously. Restarted on Prednisolone at 40mg an advised to split azathioprine to 50mg am and 50mg evening. Again the pred came to an end and symtpoms all back again. Each time CRPs negatve but feacal calprotectin shows significant inflamation. Consultant due to see me in Jan to discuss Humira but why on earth is my CRP not raised? Any guidance is greatly appreciated. :yfaint: