I started on Remicade back in '05. It took about 8 months to get things under control but once it did it was a wonderful drug for me. I was on a low dose too. (365mg). just this last dec. i noticed that i had many symptoms return and the dose was increased to 420mg. unfortunately, it only lasted a few weeks and not 8. then i had a severe flare up with high fever and all. they thought i had a bacterial infection, but after a CAT scan said it was just the Crohn's. another increase to 800mg and it only lasted 2 weeks before symptoms returned. it was a long 6 weeks and in that time had a colonscopy which i believe aggravated Fred(my fistula... i named it in the beginning in '01). it has been pretty painful, abscessed and all that not so fun stuff. tues i had remicade, and the next day the fistula was nearly gone and this morning my stomach is feeling pretty good too. we are hoping that the entocort helps me get through, at least my wedding on june 9th and after i'll prob have to switch over to Humira. but now i'm debating... if the remicade keeps the fistula away, i can totally deal with everything else. that has by far been the worst part for me. hope this gives you some hope. cause the remicade gave me nearly 8 amazing yrs.