You gotta love science -- growing intestinal organoids as a study platform.
University of Michigan scientists are embarking on a new program that grows human intestinal organoids from stem cells that they are coaxed into becoming a "guts in a dish". These are BB-sized balls comprised of the epithelium structures of the human gut. They can then introduce various bacteria into this oxygen-free environment and study the interaction of the immune cells with the bacteria.
The platform is called Novel, Alternative Model Systems for Enteric Diseases, or NAMSED, and can be scaled up into large arrays to study many intestinal diseases, including Crohn's, and to screen new drugs.
University of Michigan scientists are embarking on a new program that grows human intestinal organoids from stem cells that they are coaxed into becoming a "guts in a dish". These are BB-sized balls comprised of the epithelium structures of the human gut. They can then introduce various bacteria into this oxygen-free environment and study the interaction of the immune cells with the bacteria.
The platform is called Novel, Alternative Model Systems for Enteric Diseases, or NAMSED, and can be scaled up into large arrays to study many intestinal diseases, including Crohn's, and to screen new drugs.
