I've been tapering off prednisone and started Humira about 5 weeks ago. When I was on 40 mg of pred I felt at my best. But now that I'm tapering my Crohn's symptoms are creeping back. Is that normal? I figured the Humira would have been kicking in by now. I'm feeling a little discouraged because this disease has just been awful to me. I want to feel normal again....