I have been diagnosed with Crohns for about 10 months now. I have tapered off of prednisone two different times. Within a week of both of those times, I had a flare up. The only thing that seems to work is prednisone. I was wondering how long different people have been on it and what dosage they took. Unlike many others that take this drug, I don't have any immediate side effects. I'm going to my GI tomorrow to see what he says about it.