My daughter has been on Humira for about 14 weeks now. At 11 weeks she went to weekly doses. She is just the same, hasn't improved. She lost some weight, we got it back on her, the Dr suggested adding methotrexate injections. We were leaving on vacation and only got the pill form because we had no time to get to the Dr office for instruction on the injections. From what I have read, the pills do little aside from their side effects. My daughter, 12 told me yesterday that she would rather live in Heaven sometimes where she could play abd be happy w/o pain. This is a very lonely disease. We don't have dont have insurance, so remicade infusions are an option if we can get the meds free, but the cost for the infusions may break us. Any one find success in reaching remission on the combo of Humira and methotrexate?