Yeah, I knew metho could cause reproductive issues, but I'm past that these days... No, my point was that these drugs can pass from partner to partner in bodily fluids... Now, a person who is knowingly taking Imuran is required to have routine blood tests... to see if its doing any harm. Their partner, who might absorb those same drugs from exchanged fluids, isn't aware nor tested for these harmful side effects. Thats the reason I was given to practice only safe sex... Now, some docs might consider the risk too minimal to urge the precaution... Maybe its best to ask your own dr.