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Inflammation markers

So the NP says I have no inflammation markers in my blood work. I am wondering how can that be when I have pain as things go through my system and my stools are like water, no form whatsoever.
 

Scipio

Well-known member
Location
San Diego
The inflammation markers don't always work. The primary inflammation marker in the blood is CRP. It is often elevated when Crohn's is active but not always. I'm one of those for whom CRP doesn't work as a marker for the state of my Crohn's. No matter whether I'm in total remission or stuck in a painful flare, my CRP is always flat normal (<3.0).
 

my little penguin

Moderator
Staff member
Same here my kiddos bloodwork is always normal except if he has a massive infection
But inflammation from crohns or arthritis- completely normal bloodwork
Thankfully they can see the inflammation in his joints
Gi tract is a little trickier
 
Thanks for the info. I am not real pleased with that NP because she treated me like it’s all in my head when my body is telling me otherwise. Not sure how you get them to listen to you though. Sent me home without helping me at all. These are the medical people I don’t like and can do without.
 

crohnsinct

Well-known member
SAME! My daughters don't show inflammation in blood labs unless they are really sick to the point of sepsis. Fecal calprotectin is usually the test that will show inflammation in the GI tract. But even that is not telltale for a few people.
 

Lady Organic

Moderator
Staff member
same here. I am more precise and accurate then blood and calprotectine tests in recognizing a debuting stage flare. Experienced and qualified GI teams should know that. Insist on seeing the GI. If the nurse refuses and continues making you feel bad, inadequate and make you risk a deterioration of your condition, consider a new GI team. IBD is a lifelong disease, it is important to feel good and to get along with our caregivers.
 
Hi Everyone, That is true that the blood or serum inflammatory markers do not truly represent the inflammatory activity in the body, studies have shown that 15 to 20% of cases this seems to occur. For ulcerative colitis a better marker is fecal calprotectin, but please make sure your insurance covers the cost for this, some dont in certain states. For Crohn's disease fecal calpro is helpful if the disease is mainly in the colon. I hope this answers your questions.

Also, I strongly recommend seeing a GI specialist atleast once a year or every 6 months, avoid only seeing primary care providers or NP's.
 
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