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Infliximab levels

Hi everyone.
Im a 50 year old female on infliximab for Crohns since Sept 2022.
My bloods taken on jan 5th show remicade level at 8.3. Antibodies also detected. My gastroenterologist says the drug level should be higher and she wants to see me in a few weeks.
Should I be worried? What are the acceptable drug levels?
I am symptom free.
Many thanks.
Mairead
 

Scipio

Well-known member
Location
San Diego
Many GIs like to see Remicade levels in the 5 to 10 range. Some prefer higher. So an 8.3 is normally a solid number, but perhaps your doc is one of those who likes the numbers to be a bit higher, and/or perhaps the antibody level is a bit worrying, thus the need to to boost the Remicade a bit to be sure to overpower the drug inactivating effects of the antibodies and keep you symptom free.
 
Thanks for your reply Scipio. Its reassuring.
I dont know what GI has planned for me. Hopefully leave me on remicade. I wouldnt like to have to switch meds after only 6 months. Im just so glad to be symptom free apart from mild cramps sometimes.
Last year was difficult. 2 hospital stays due to fistulising infections.
🤞🤞all will be well
 
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