Help!
It's been almost a month and HAP is still not approving the PA for my son's Humira. He is 8yrs old, and 68lbs (30kg).
He had 160mg day 1, 80mg day 14, he'll get 40mg on Wednesday (day 28), and then dr wants 40mg EVERY week. We realize this is higher than adult dosing at 40 every other week. He failed Remicade badly, and said he clears the TNF alpha inhibitors faster than normal, and he had a "through the roof" number of antibodies to it. He needs this dose to prevent that from happening again, and especially since this is the last "approved" drug for his age.
Hap only wants to cover 20mg EVERY OTHER week. They say the dose dr wants him on is dangerous. If anyone has any supporting literature about this type of dosing in this age/weight patients, PLEASE let me know. I am so worried that if my son doesn't get this dose, he will clear too quickly and develop antibodies. I am panicked that this is the last drug he can use, even though there are others for adults, and they will probably use them because we won't have a choice.
Any help on this is appreciated!!
It's been almost a month and HAP is still not approving the PA for my son's Humira. He is 8yrs old, and 68lbs (30kg).
He had 160mg day 1, 80mg day 14, he'll get 40mg on Wednesday (day 28), and then dr wants 40mg EVERY week. We realize this is higher than adult dosing at 40 every other week. He failed Remicade badly, and said he clears the TNF alpha inhibitors faster than normal, and he had a "through the roof" number of antibodies to it. He needs this dose to prevent that from happening again, and especially since this is the last "approved" drug for his age.
Hap only wants to cover 20mg EVERY OTHER week. They say the dose dr wants him on is dangerous. If anyone has any supporting literature about this type of dosing in this age/weight patients, PLEASE let me know. I am so worried that if my son doesn't get this dose, he will clear too quickly and develop antibodies. I am panicked that this is the last drug he can use, even though there are others for adults, and they will probably use them because we won't have a choice.
Any help on this is appreciated!!