Yah, people with NOD2 mutation tend to have worse disease, they'll have more stricturing too as a result. NOD2 doesn't have anything to do with stricturing directly afaik, it's involved in bacterial recognition and it directs autophagy to kill bacteria. But a NOD2 defect just gives you a worse disease prognosis, which is gonig to make it more likely you have strictures.Kiny - not sure if this question even really makes sense but... I believe a mutation in NOD2 may indicate a greater likelihood of fistulizing disease but does it also indicate a greater likelihood of stricturing disease? Or is there no connection between NOD2, fistulizing or stricturing??
I should have seen pictures of crohn's disease earlier, I might have taken my disease more serious. It's a shame that not more people know what a serious disease this is, it needs more attention.Like, those photos aren't for the squemish