I've been on imuran for a little over a year now at 100mg. Since the beginning of this year, every month I get super itchy mostly on my arms/legs but no rash. Super frustrating because I'm 23, starting a new job soon and never change anything in my diet or home life such as detergent, shampoo and body wash etc. is it the imuran? Not sure what to do but I can't keep doing this for forever. My dermatologist and obgyn think I should go on a biologic anyway to be safer. Its hard to get answers because without a rash my GP and GI have no idea whats causing it and my blood work and liver panel look good! Just looking for advice on what to do and if this has happened to others and if I should switch to a biologic like humira? Thank you!