Hi. I have had chron's since 2003 and since then i have tried everything. Started with asacol...6mp....azathioprine...pred after pred after pred ... Then in 2005 i was started on remicade and boy did it work. Everything was going fine until a couple of months ago my doc said she wanted do a colonoscopy just because they wanted to see how i was doing. I said ok...worst decision ever, the damn doc doing the proceedure perforated my bowel. I was hospitalised and woken at 2am telling me i had to have surgery. I had been ok until then so i fought and refused surgery. They told me if my bowel got infected it could be life threatening. But i didnt feel that bad really just pain. They put me on polymeric diet and flagyl/cipro. After 3 weeks my bowel healed but my chron's went mental. Since then i have been back in hospital 3 times because now the remicade has stopped working. Im on 40mg of pred and still in terrible pain also lots of D, which ive never suffered with before. My doc now says iust have surgery but i have convinced him to try me on humira. My question is if your body stops responding to remicade will humira work? My doc doesnt seem to think it will. Oh and if anyone knows the doc that perforated me throw rocks at him!!