Hi again, Rose! When I've got the days off to spare, I always try to take 3 days off of work for scopes. A day before to do prep, obviously the day of the scope, and I also take off the day after - sometimes, it's a bit painful the day after the scope once the pain meds have worn off. I sometimes can feel the spots where they've taken biopsies, and/or have trapped wind pain from the air they pump into the colon during the scope. As far as having diarrhea from the prep, though, I'm usually fine in that regard by the following day. If anything, I tend to not go at all for a few days following the scope - I presume it's because I was so cleaned out that it takes a few days for my system to "fill up" with stool again, or something like that. So yeah, for me I do take the following day off but it's because of pain, not because of bathroom trips.