I started LDN for Crohn's colitis five weeks ago, starting at 1ml liquid and gradually got up to 3ml a week ago. The past few days I have been experiencing worsening diarrhea, particularly during the night (a few hours after I have taken my LDN). Has anyone else experienced this when starting LDN? Do you sometimes get worse before you get better? My GI is not in favour of LDN which makes it harder to stick with it. I have been up practically all night the past three nights and having to drag myself into work. Not good and I don't want to take immodium all the time. If anyone can offer any thoughts, I would be very grateful.