i'm assuming my crohn's is moderate to severe because i just started humira 1 box ago.....i gave myself an 80mg shot this morning and i'm losing my shit. Humira is fine, it doesn't hurt, it's user friendly and it's much better than taking pills IMO. I've been flared up since april and had to take myself off the prednisone, i have the worst reactions from it and my doctor says that's the only treatment. I don't know if i'm going to have to go back on it if the humira doesn't work, but i'm losing hope. This is a terrible way to live and trying to stay positive only goes so far. I'm 36, diagnosed about 10 years ago....1 surgery back then and i suffer a lot.