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MTX- 15 hours since my 1st injection

I took my first injection of MTX yesterday afternoon. Having read about all the immediate side effects I was a bit worried. 15 hours later and no nausea or headaches or any of the other typical negative effects. My only issue is that I'm constipated. I'm used to running to the bathroom 25-20 times a day. Is constipation a typical issue for people on MTX?