I've just had two doses of Prednisone so far, 40 mg. I wake up in the middle of the night soaked in sweat. Is this how it's going to be? I haven't been on it for like six years, and I don't remember it being this bad. On the plus side, there was a definite "plunk" sound in the bathroom this morning that I hadn't heard in years, and my bloated belly is gone.