Omvoh (mirikizumab) (similar to Stelara) approved for UC but not for Crohns??

[Kannassee]

Well I just found out that Omvoh (mirikizumab) was approved for UC but not for Crohns.

It seems that every other biologic that works for UC also works for Crohns, so I am wondering why they did not approved for Crohns.... the more options the better (well at least for the patients) since the biologics costs are supposed to come down.

I am now on Stelera, and it did nothing for me until they upped up the dose to 1 shot every 4 weeks.

I just had my Calprotectin test done and its around 200 so that is good news. Every 4 weeks did the trick for me. It still is not as good as Remicade (Calc around 50 on a high dose) but I feel much better since I am fine and I am not catching colds all the time.
With Remicade I was all the time with a cold and I had to take a lot of antibiotics, 2 or 3 weeks after I stopped them the infections got back.

But the problem is that it was a battle to get Stelara approved to every 4 weeks by the insurance company. This year probably it will be the same. Considering that its around 25k every month I don't blame them.

 

[my little penguin]

Lilly will pursue approval in Crohn’s in 2024, when it will submit a marketing application to the FDA and other regulatory agencies.

So it will go to the fda this year sometime

After FDA snub, Lilly's mirikizumab looks to regain momentum with phase 3 Crohn's win

After the FDA passed on an approval for mirikizumab in ulcerative colitis earlier this year because of manufacturing shortfalls, the Eli Lilly drug is gaining new momentum with a win in a | A majority of Crohn's disease patients experienced a clinical response and clinical remission after...

www.fiercepharma.com

 

[Kannassee]

Well that would be great if they do.!!!

 

[asadmom]

Well I just found out that Omvoh (mirikizumab) was approved for UC but not for Crohns.

It seems that every other biologic that works for UC also works for Crohns, so I am wondering why they did not approved for Crohns.... the more options the better (well at least for the patients) since the biologics costs are supposed to come down.

I am now on Stelera, and it did nothing for me until they upped up the dose to 1 shot every 4 weeks.

I just had my Calprotectin test done and its around 200 so that is good news. Every 4 weeks did the trick for me. It still is not as good as Remicade (Calc around 50 on a high dose) but I feel much better since I am fine and I am not catching colds all the time.
With Remicade I was all the time with a cold and I had to take a lot of antibiotics, 2 or 3 weeks after I stopped them the infections got back.

But the problem is that it was a battle to get Stelara approved to every 4 weeks by the insurance company. This year probably it will be the same. Considering that its around 25k every month I don't blame them.

When you said infections would be recurring, do you mean pneumonia caused by the cold?

 

[Kannassee]

not really pneumonia.

I got a bad cold, and then in a couple of days cough got productive and the phlegm got yellow or green.....then I got antibiotics and then it cleared right away and after the course of antibiotics 2 or 3 weeks later the same thing happened again and again.

But I never got fever or pneumonia, just asthma. Before that did not happen.

This year no problems at all. Maybe it was not the Remicade and it was just a coincidence.