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(Podcast) Pioneering Researcher Alessio Fasano on Gluten, Autoimmunity & Leaky Gut

It's an honor to welcome Dr. Alessio Fasano as a guest on the show. Dr. Fasano is globally recognized for his pioneering research in the fields of Celiac disease and gluten intolerance. In 2003, he published the groundbreaking study in the Annals of Medicine that established the prevalence rate of celiac disease at one in 133 people in the U.S - a rate nearly 100 times greater than the previous estimate. He also headed up a team that discovered (in 2000) the ancient molecule zonulin, which regulates the permeability of the intestine and is know known to be a major player in the condition known colloquially as "leaky gut".

Dr. Fasano has been featured in hundreds of interviews in media outlets such as The Wall Street Journal; NPR; New York Times Magazine; National Geographic, Bloomberg News; USA Today; Los Angeles Times; “Good Morning America”; The Globe and Mail; Vogue; and numerous health-related websites and magazines.

On a personal note, Dr. Fasano is one of my research heroes and his work has had a huge impact on my understanding of the gut and autoimmune disease. We’re extremely fortunate to have him as a guest on the show. I hope you’re as excited about this as I am!


Zonulin, regulation of tight junctions, and autoimmune diseases

Zonulin and Its Regulation of Intestinal Barrier Function: The Biological Door to Inflammation, Autoimmunity, and Cancer

Intestinal zonulin: open sesame!

https://todayspractitioner.com/wp-content/uploads/2018/08/Fasano.pdf An interview.

https://medicalxpress.com/news/2017-04-evidence-linking-leaky-gut-chronic.html Researchers provide evidence linking 'leaky gut' to chronic inflammation


https://www.jillcarnahan.com/2013/07/14/zonulin-leaky-gut/ Zonulin: A Discovery That Changed the Way We View Inflammation, Autoimmune Disease and Cancer

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