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Predisone and tummy problems

You think I'd know this, being on and off predisone for about 25 years. I stopped budesonide and started predisone last week. I am currently on 40mg/day. I take it on a full stomach. However, it seems for an hour or two after I take the predisone, I am nauseous and my stomach feels like it is churning. And then 3-4 hours later, my gut is topsy-turvey.

Is this normal? I didn't think it was. I don't remember it from the past, but I've been mainly on budesonide for the past several years instead of predisone. Also, I'm on the predisone for a back issue (and also my Crohn's), which is why I switched from the budesonide.
 
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