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Prednisone 40mg, all at once or spread? Reason for question in thread

The reason I’m asking why I should spread is because :
When I take all at once in the morning, I end up waking in the middle of the night and pooping 5 times. Then waking up tired and weak before my next dose kicks in.
Yesterday I tried splitting. 50% at morning and 50% at late afternoon. And 0 trips to bathroom at nighttime, infact I’m still not going to the bathroom today.
Opinions? Should I ask doc?

my little penguin

Staff member
Talk to your doc
They can instruct on what is ok to do in your case
Ds’s Gi has him split the dose 50-50 until he gets under 10 mg the then just dose in the AM ....
But everyone’s doc is different