I raised this question in another post, but thought that it required a separate posting to do the question justice. For everyone who has been prescribed both prednisone AND imuran, which provided you the most benefit? Which gave you the worse side effects? Have you or your doctor ever listed the pros and cons of one versus the other? If you had to choose only one of these, which would you pick and why? The point of all this is that my GI wants to wean me off of the prednisone (because of the long term side effects) then put me on Imuran if my symptoms persist. Just wondering if anyone else has gone that route, and if so, did they see a big difference in the pros and cons of one versus the other??