kiny
Well-known member
- Joined
- Apr 28, 2011
- Messages
- 3,465
All the studies that scare people regarding emulsifiers, polysorbate 80, maltodextrin, and tell people to eat more fibre, based on their studies in petri dishes, need to start explaining how EN full of emulsifiers, maltodextrin, and complete lacking in fibre are the most effective treatment for inducing remission in crohn's disease.
We went from low-residue diet and elemental diet recommendations for crohn's disease based on clinical evidence in the 90s, to dieticians telling patients to stuff themselves with fibre, prebiotics, probiotics etc, to "feed the good bacteria". Animals with transient microbiomes are doing just fine.
The Elemental formulas that contain most of these emulsifiers and no fibre at all, are ironically some of the most effective in bringing down inflammation.
We went from low-residue diet and elemental diet recommendations for crohn's disease based on clinical evidence in the 90s, to dieticians telling patients to stuff themselves with fibre, prebiotics, probiotics etc, to "feed the good bacteria". Animals with transient microbiomes are doing just fine.
The Elemental formulas that contain most of these emulsifiers and no fibre at all, are ironically some of the most effective in bringing down inflammation.
Fibre has long been advocated as a beneficial nutrient for
Crohn's disease patients despite well-designed RCTs failing to prove
any profound benefit. Despite their clinical effectiveness
and amelioration of gut inflammation, the large majority of the EEN
formulas analysed here (80%) lack any fibre.
Maltodextrin, carrageenan, carboxymethyl cellulose and polysorbate 80 have all been associated with gut inflammation. We have shown here that all EEN formulas, which reported their carbohydrate source, contain excessive amount of modified starches, including maltodextrin, which are disproportionately higher than a healthy
person would potentially consume daily as part of their habitual diet.
We therefore propose that authors making dietary recommendations based on the current epidemiological evidence, animal and in vitro experiments need to have supportive in vivo evidence in human Crohn's disease before such wide ranging dietary
restrictions are introduced to clinical practice.
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