I was diagnosed with UC several years ago and "re-diagnosed" with Crohn's a few months ago (after switching to a new GI doc). My symptoms have gotten progressively worse over the years, and I now have pretty aggressive perianal Crohn's (fistulas, abscesses, etc.) and ileocolic Crohn's. Here is where I am confused. My CRP and sed rates have always been within "normal" to slightly high levels. I also had the Prometheus test which came back negative or inconclusive. Despite this bloodwork, my MRI and CT clearly shows indications of Crohn's (and I have already had surgery for the abscess and fistulas). Is this common to have no indication of Crohn's/UC in the blood but still clearly have the disease?